Matthew McConaughey

(Cooper)

Anne Hathaway

(Brand)

Michael Caine

(Professor Brand)

Jessica Chastain

(Murph)

Casey Affleck

(Tom)

Wes Bentley

(Doyle)

Topher Grace

(Getty)

Mackenzie Foy

(Murph (10 Yrs.))

Ellen Burstyn

(Murph (older))

John Lithgow

(Donald)

Bill Irwin

(TARS (voice))

David Gyasi

(Romilly)

Timothée Chalamet

(Tom (15 Yrs.))

Matt Damon

(Mann)

Josh Stewart

(CASE (voice))

Leah Cairns

(Lois)

Liam Dickinson

(Coop)

Francis X. McCarthy

(Boots)

William Devane

(Williams)

Andrew Borba

(Smith)

Elyes Gabel

(Administrator)

David Oyelowo

(School Principal)

Collette Wolfe

(Ms. Hanley)

Jeff Hephner

(Doctor)

Russ Fega

(Crew Chief)

Lena Georgas

(Nurse Practitioner)

Brooke Smith

(Nurse)

Flora Nolan

(Girl on Truck)

Griffen Fraser

(Boy on Truck)

Kristian Van der Heyden

(Scientist (uncredited))

William Patrick Brown

(NASA Employee (uncredited))

Benjamin Hardy

(NASA Scientist (uncredited))

Joseph Oliveira

(Astronaut (uncredited))

Alexander Michael Helisek

(Construction Boss (uncredited))